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Researchers at Duke University identified ALDH4A1, a metabolic enzyme that plays a critical role in cellular energy production and cancer suppression.
Key points:
ALDH4A1 stabilizes a protein complex that imports pyruvate into mitochondria, fueling healthy cell function.
Loss of ALDH4A1 leads to the Warburg effect, where cancer cells rely on inefficient glycolysis.
Tumors often show reduced ALDH4A1, and restoring its activity slows tumor growth.
The study suggests ALDH4A1 could be a therapeutic target to cut off energy supply to cancer cells while preserving normal ones.Researchers at Duke University identified ALDH4A1, a metabolic enzyme that plays a critical role in cellular energy production and cancer suppression. Key points: ALDH4A1 stabilizes a protein complex that imports pyruvate into mitochondria, fueling healthy cell function. Loss of ALDH4A1 leads to the Warburg effect, where cancer cells rely on inefficient glycolysis. Tumors often show reduced ALDH4A1, and restoring its activity slows tumor growth. The study suggests ALDH4A1 could be a therapeutic target to cut off energy supply to cancer cells while preserving normal ones.0 Comentários ·0 Compartilhamentos ·21KB Visualizações -
COLOSSAL TURKEY & BRIE HOLIDAY MELT
Ingredients:
1/2 lb sliced roasted turkey
4 oz brie cheese, sliced
4 slices thick sourdough or rustic bread
1/4 cup cranberry sauce
Handful of arugula or spinach
Butter for grilling
Instructions:
1️⃣ Butter bread slices and layer turkey, brie, cranberry sauce, and greens.
2️⃣ Grill sandwich in skillet or press until bread is golden and cheese is melty.
3️⃣ Slice and serve warm — holiday flavors in every bite!
Prep: 10 min | Cook: 10 min | Total: 20 min | Serves: 2COLOSSAL TURKEY & BRIE HOLIDAY MELT 🦃🧀🍞 Ingredients: 🦃 1/2 lb sliced roasted turkey 🧀 4 oz brie cheese, sliced 🍞 4 slices thick sourdough or rustic bread 🍒 1/4 cup cranberry sauce 🌿 Handful of arugula or spinach 🧈 Butter for grilling Instructions: 1️⃣ Butter bread slices and layer turkey, brie, cranberry sauce, and greens. 2️⃣ Grill sandwich in skillet or press until bread is golden and cheese is melty. 3️⃣ Slice and serve warm — holiday flavors in every bite! 🔥 Prep: 10 min | Cook: 10 min | Total: 20 min | Serves: 20 Comentários ·0 Compartilhamentos ·21KB Visualizações