Tuberculosis has plagued humanity for centuries, killing more people each year than nearly any other infectious disease. But scientists may have finally turned the tide. A new mRNA vaccine, dubbed mRNACV2, has demonstrated strong effectiveness in preclinical trials—triggering a powerful immune response in mice and dramatically reducing the bacterial load in their lungs. This represents a major leap beyond the current BCG vaccine, which offers limited protection and hasn't changed much since its introduction in 1921. What makes this breakthrough especially significant is the use of mRNA technology—the same approach that powered COVID-19 vaccines. This marks the first time mRNA has shown such promise against a bacterial infection, not just viruses. With human trials now on the horizon, the medical community is hopeful that this could lead to a durable, global solution for TB—a disease that still kills over 1 million people annually despite being preventable and treatable. #mRNAVaccine #TBCure #MedicalBreakthrough #InfectiousDiseases #PublicHealthRevolution