Scientists in Japan have officially begun human trials of TRG-035, a drug that could allow people to regrow missing teeth—naturally. Inspired by animals like sharks that regenerate teeth throughout life, this breakthrough targets the USAG-1 protein, which normally suppresses tooth formation in humans.
The Phase 1 clinical trial at Kyoto University Hospital involves 30 adults who are missing at least one tooth. The next phase aims to help children with congenital conditions where permanent teeth never grow at all. If successful, this could replace dental implants entirely by the year 2030—making tooth loss a fixable problem through biology, not surgery.
#ToothRegrowth #DentalBreakthrough #HumanTrials #MedicalInnovation #RegenerativeMedicine
The Phase 1 clinical trial at Kyoto University Hospital involves 30 adults who are missing at least one tooth. The next phase aims to help children with congenital conditions where permanent teeth never grow at all. If successful, this could replace dental implants entirely by the year 2030—making tooth loss a fixable problem through biology, not surgery.
#ToothRegrowth #DentalBreakthrough #HumanTrials #MedicalInnovation #RegenerativeMedicine
Scientists in Japan have officially begun human trials of TRG-035, a drug that could allow people to regrow missing teeth—naturally. Inspired by animals like sharks that regenerate teeth throughout life, this breakthrough targets the USAG-1 protein, which normally suppresses tooth formation in humans.
The Phase 1 clinical trial at Kyoto University Hospital involves 30 adults who are missing at least one tooth. The next phase aims to help children with congenital conditions where permanent teeth never grow at all. If successful, this could replace dental implants entirely by the year 2030—making tooth loss a fixable problem through biology, not surgery.
#ToothRegrowth #DentalBreakthrough #HumanTrials #MedicalInnovation #RegenerativeMedicine
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